The innovative evolution of cancer gene and cellular therapies

P. Lam
,
Ghazala Khan
,
R. Stripecke
,
K.M. Hui
,
N. Kasahara
,
Kah-Whye Peng

National Cancer Centre
,
Hannover Medical School
,
University of California at Los Angeles

Research Output: Contribution to journal Article Peer-review

Sustainable Development Goals

SDG 3 Good Health and Well

Abstract

We provide an overview of the latest developments in cancer gene therapy--from the bench to early-stage clinical trials. We describe the most recent work of worldwide teams including experienced scientists and clinicians, reflecting the recent emergence of gene therapy from the 'Valley of Death'. The treatment efficacy of clinical gene therapy has now been shown in a number of diseases including cancer and we are observing a renewed interest by big pharmaceutical and biotechnology companies most obviously demonstrated by Amgen's acquisition of Biovex for up to USD$1 billion. There is an opportunity to be cautiously hopeful regarding the future of gene therapy in the clinic and we review here some of the most recent progress in the field.

Publication Information

Output type

Research Output: Contribution to journal Article Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 141-149

Journal (Volume, Issue Number)

Cancer Gene Therapy (Volume 20, Issue 3)

Publication milestones

Published - 01/02/2013

Publication status

Published - 01/02/2013

ISSN

0929-1903

External Publication IDs

handle.net: 10547/578855
Scopus: 84875211121

Access to documents

10.1038/cgt.2012.93

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