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Speckle tracking in intracardiac echocardiography for the assessment of myocardial deformation

  • Yong Yue
    ,
  • J.W. Clark
    ,
  • D.S. Khoury
Research Output: Contribution to journal Article Peer-review

Abstract

Intracardiac echocardiography has proven to be useful for online anatomical imaging during catheterization. Our objective was to develop a speckle tracking method for myocardial motion estimation from intracardiac echocardiographic image sequences in order to provide a mean for regional functional imaging. Our approach was to solve two problems in motion estimation from two-dimensional intracardiac echocardiographic image sequences: non-rigid myocardial deformation and speckle decorrelation. To achieve robust noise resistance, we employed maximum likelihood estimation while fully exploiting ultrasound speckle statistics, and treated the maximization of motion probability as the minimization of an energy function. Non-rigid myocardial deformation was estimated by optimizing this energy function within a framework of parametric elastic registration. Evaluation of the method was carried out using a computer model that synthesized echocardiographic image sequences, and subsequently an animal model that provided continuous intracardiac echocardiographic images as well as reference measurements using sonomicrometry crystals. In conclusion, accurate estimation of regional myocardial deformation from intracardiac echocardiography by novel speckle tracking is feasible. This approach may have important clinical implications for multimodal imaging during catheterization.

Publication Information

Output type

Research Output: Contribution to journal Article Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 416-425

Journal (Volume, Issue Number)

IEEE Transactions on Biomedical Engineering (Volume 56, Issue 2)

Publication milestones

  • Published - 01/10/2008

Publication status

Published - 01/10/2008

ISSN

0018-9294

External Publication IDs

  • handle.net: 10547/250941
  • Scopus: 64249115261

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