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In vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic acid

  • Fuming Yang
    ,
  • Samson A. Oyeyinka
    ,
  • Weili Xu
    ,
  • Ying Ma
    ,
  • Shaobo Zhou
  • Harbin Institute of Technology
    ,
  • University of Ilorin
Research Output:
Contribution to journal
Article
 Peer-review

Open access

Abstract

Phytosterols are bioactive components capable of reducing cholesterol level in serum and reducing risk of arteriosclerosis. In this study, conditions for the synthesis of maximum yield of phytosterol linoleic ester (PLE) was optimized and the physicochemical properties and in vitro bioaccessibility of the PLE were assessed. Under the optimized condition of 1:1.1 mol ratio of phytosterol and linoleoyl chloride at 80 °C for 1.5 h, the conversion rate of phytosterol reached 96.1%. Its solubility in oil increased 20 times, up to 33.8%. Also, peroxide value of PLE was much lower than linoleic acid (32.9 and 47.0 mmol/kg), which means better oxidative stability. Bioaccessibility of PLE was affected by time, concentration of bile extract, and dissolved medium. It was 4.93% alone, increased by 2.5 times compare to phytosterol; or 53.46% in oil, under the condition of 40 mg/mL bile extract for 120 min. In conclusion, under the tested condition, phytosterol conversion rate, its solubility in oil and bioaccessibility were improved significantly. The method showed great potential in manufacture high quality and quantity of PLE.

Publication Information

Output type

Research Output:
Contribution to journal
Article
 Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 265-271

Journal (Volume, Issue Number)

LWT (Volume 92, Issue 2)

Publication milestones

  • Published - 14/02/2018

Publication status

Published - 14/02/2018

ISSN

0023-6438

Publication IDs

  • handle.net: 10547/622511
  • Scopus: 85042383607

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