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Imaging quality assessment of different AFM working modes on living cancer cells

  • Guoliang Wang
    ,
  • Baishun Sun
    ,
  • Xiaomin Wu
    ,
  • Wenxiao Zhang
    ,
  • Yingmin Qu
    ,
  • Zhengxun Song
  • Changchun University of Science and Technology
Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Abstract

Since the invention of atomic force microscope (AFM) in 1986, its capabilities in biophysical research, such as living cell imaging, molecule imaging and recognition and drug treatment analysis, have been deeply investigated. Various types of working modes of atomic force microscopy have been employed for imaging and analyzing living cells. The physical properties of living cells can be directly illustrated by its good resolution images. In this paper, the applications of three AFM working modes including contact, tapping and quantitative imaging (QI) modes for the investigation of living lung cancer cells (A549) are presented. Meanwhile, the quality of images of the cells obtained by different working modes is compared through the image quality assessment (IQA) methods.

Publication Information

Output type

Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Original language

English

Publication milestones

  • Published - 02/02/2020

Publication status

Published - 02/02/2020

Publisher

Institute of Electrical and Electronics Engineers Inc., United States

External Publication IDs

  • handle.net: 10547/624159
  • Scopus: 85078818855

Host publication title

2019 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)

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