Effect of astragalus polysaccharides on cancer cells studied by AFM

Zhengcheng Lu
,
Zuobin Wang
,
Dayou Li
,
Wenyu Zhu
,
Rui Wang
,
Kaige Qu

Changchun University of Science and Technology
,
University of Bedfordshire

Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Open access

Sustainable Development Goals

SDG 3 Good Health and Well

Abstract

As a traditional Chinese medicine, astragalus and its products are used in cancer treatment aiming to reduce the side effects of chemotherapy. Cells are the most basic unit of living organisms, and AFM directly obtains information from living cells on the micro/nano scale. Therefore, the use of AFM to study the interaction between astragalus and cells is conducive to a full range of drug efficacy evaluation and provides a new way for drug development. In this paper, astragalus polysaccharides were extracted from astragalus, which were diluted into solutions of different concentrations. Combined with the MTT experiment, the effects of Astragalus polysaccharide on cancer cells and benign cells were studied by AFM.

Publication Information

Output type

Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 51-54 (4 pages)

Publication milestones

Accepted/In press - 01/07/2021
Published - 17/11/2021

Publication status

Published - 17/11/2021

Publisher

Institute of Electrical and Electronics Engineers Inc., United States

Publication series

Publication series name: 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings