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Determination of optimal curing conditions for imaging single lung cancer cells by atomic force acoustic microscope

  • Xuan Wang
    ,
  • Yujing Zhao
    ,
  • Wenxiao Zhang
    ,
  • Ying Wang
    ,
  • Liguo Tian
    ,
  • Xinyue Wang
  • Changchun University of Science and Technology
Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Abstract

This paper presents a method for the determination of optimal curing conditions for the imaging of single lung cancer cells by atomic force acoustic microscope (AFAM). The cellular morphology, height and surface roughness of the cells treated with different concentrations of paraformaldehyde and methanol and durations were observed using an AFAM. The experimental results showed that the A549 cells solidified with 4% paraformaldehyde for the period from 30min to 60min were close to the profiles of living cells. The cells solidified with 4% paraformaldehyde for 10min were beneficial to obtain subsurface structures.

Publication Information

Output type

Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 83-86

Publication milestones

  • Published - 29/11/2018

Publication status

Published - 29/11/2018

Publisher

Institute of Electrical and Electronics Engineers Inc., United States

ISBN (Print)

9781538662144

External Publication IDs

  • handle.net: 10547/623822
  • Scopus: 85059989353

Host publication title

2018 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)

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