Skip to search boxSkip to navigationSkip to main content

Controlled self-assembly of lambda-DNA networks with the synergistic effect of a DC electric field

  • Mingyan Gao
    ,
  • Jing Hu
    ,
  • Ying Wang
    ,
  • Mengnan Liu
    ,
  • Jianfei Wang
    ,
  • Zhengxun Song
  • Changchun University of Science and Technology
Research Output: Contribution to journal Article Peer-review

Abstract

Large-scale and morphologically controlled self-assembled λ-DNA networks were successfully constructed by the synergistic effect of a DC electric field. The effect of DNA concentration, direction, and intensity of the electric field, even the modification of the mica surface using Mg2+ on the characteristics of the as-prepared DNA networks, were investigated in detail by atomic force microscopy (AFM). It was found that the horizontal electric field was more advantageous to the formation of DNA networks with more regular structures. At the same concentration, the height of DNA network was not affected significantly by the intensity change of the horizontal electric field. The modification of Mg2+ on mica surface increased the aggregation of DNA molecules, which contributed to the morphological change of the DNA networks. Furthermore, DNA molecules were obviously stretched in both horizontal and vertical electric fields at low DNA concentrations.

Publication Information

Output type

Research Output: Contribution to journal Article Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 9809-9818

Journal (Volume, Issue Number)

Journal of Physical Chemistry B (Volume 123, Issue 46)

Publication milestones

  • Published - 04/11/2019

Publication status

Published - 04/11/2019

ISSN

1520-6106

External Publication IDs

  • handle.net: 10547/624105
  • handle.net: 10547/624392
  • Scopus: 85075118972

Access to documents

Publication metrics