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Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells

  • Zahara Latif Chaudhry
    ,
  • Bushra Ahmed
Research Output: Contribution to journal Article Peer-review

Abstract

The purpose of the study was to establish a suitable model to study Parkinson’s disease (PD) pathogenesis in differentiated dopaminergic neurons (dDCN). The specific aim was to demonstrate the involvement of the caspase family and to identify specific caspases which are activated by 6-hydroxydopamine (6OHD) treatment leading to death of dDCN.

Publication Information

Output type

Research Output: Contribution to journal Article Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 435-440

Journal (Volume, Issue Number)

Neurological Research (Volume 35, Issue 4)

Publication milestones

  • Published - 01/01/2012

Publication status

Published - 01/01/2012

ISSN

0161-6412

External Publication IDs

  • handle.net: 10547/302101
  • Scopus: 84875470974

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