Skip to search boxSkip to navigationSkip to main content

Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia

  • Daniel Bailey
    ,
  • Thomas Withers
    ,
  • Victoria L. Goosey-Tolfrey
    ,
  • David W. Dunstan
    ,
  • Christof A. Leicht
    ,
  • Rachael Champion
Research Output:
Contribution to journal
Article
 Peer-review

Open access

Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well

Abstract

Elevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able-bodied individuals. The effects in people with paraplegia are unknown. The study aims were to examine the acute postprandial glucose (primary aim), lipid, blood pressure, and psychological responses (secondary aims) to breaking up prolonged sedentary time in individuals with paraplegia. This was a randomized crossover design trial. Fourteen participants with paraplegia (age 51 +- 9 years, trunk fat mass 44.3 +- 7.7%) took part in the following two, 5.5-hour conditions: (1) uninterrupted sedentary time (SED), and (2) sedentary time interrupted with 2 minutes of moderate-intensity arm crank ergometer physical activity every 20 minutes (SEDACT). Standardized breakfast and lunch test meals were consumed during each condition. The outcomes were compared between conditions using linear mixed models. Glucose area under the curve (AUC) was significantly lower during the lunch postprandial period in SED-ACT vs SED (incremental AUC 1.9 [95% CI 1.0, 2.7) and 3.0 [2.1, 3.9] mmol/L∙2.5 hour, respectively, P = .015, f = 0.34). There were no differences between conditions for the breakfast or total 5.5 hours postprandial periods (P > .05). Positive affect was higher in SED-ACT than SED (P = .001). Breaking up prolonged sedentary time acutely attenuates lunch postprandial glucose and improves positive affect in people with paraplegia. This may have clinical relevance for reducing CVD risk and improving psychological well-being in this population.

Publication Information

Output type

Research Output:
Contribution to journal
Article
 Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 1398-1408

Journal (Volume, Issue Number)

Scandinavian Journal of Medicine and Science in Sports (Volume 30, Issue 8)

Publication milestones

  • Accepted/In press - 24/03/2020
  • Published - 03/04/2020

Publication status

Published - 03/04/2020

ISSN

0905-7188

Publication IDs

  • handle.net: 10547/623967
  • Scopus: 85083739393

Access to documents

Publication metrics

Metrics

Download statistics
Download count
7

PlumX, opens in new tab

16
Captures
113
Mentions
12