A dynamic feedback algorithm of AFM based on cell morphology changes

Can Cheng
,
Xinyue Wang
,
Jianjun Dong
,
Zimin Liu
,
Zuobin Wang

Changchun University of Science and Technology

Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Open access

Sustainable Development Goals

SDG 3 Good Health and Well

Abstract

The atomic force microscope (AFM) used in biological research as a powerful tool has been for many years. However, the imaging of living cells is still a problem as the sample is too high and too soft to obtain their accurate morphologies. Especially in the high-speed scanning mode, AFM does not have enough judgments to make accurate measurements at the down part of the sample. In this study, we propose an improved control method to improve the image quality of living human colon cancer cells (SW480) especially in the down part during the scanning.

Publication Information

Output type

Research Output: Chapter in Book/Report/Conference proceeding Conference contribution Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 156-159 (4 pages)

Publication milestones

Accepted/In press - 01/07/2021
Published - 18/11/2021

Publication status

Published - 18/11/2021

Publisher

Institute of Electrical and Electronics Engineers Inc., United States

Publication series

Publication series name: 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings