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The innovative evolution of cancer gene and cellular therapies

  • P. Lam
  • , Ghazala Khan
  • , R. Stripecke
  • , K.M. Hui
  • , N. Kasahara
  • , Kah-Whye Peng
  • , Barbara Guinn

    Research output: Contribution to journalArticlepeer-review

    16 Citations (Scopus)

    Abstract

    We provide an overview of the latest developments in cancer gene therapy--from the bench to early-stage clinical trials. We describe the most recent work of worldwide teams including experienced scientists and clinicians, reflecting the recent emergence of gene therapy from the 'Valley of Death'. The treatment efficacy of clinical gene therapy has now been shown in a number of diseases including cancer and we are observing a renewed interest by big pharmaceutical and biotechnology companies most obviously demonstrated by Amgen's acquisition of Biovex for up to USD$1 billion. There is an opportunity to be cautiously hopeful regarding the future of gene therapy in the clinic and we review here some of the most recent progress in the field.
    Original languageEnglish
    Pages (from-to)141-149
    JournalCancer Gene Therapy
    Volume20
    Issue number3
    DOIs
    Publication statusPublished - 1 Feb 2013

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • gene and cell therapy

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