Multi-parameter AFM characterization of INS-1 cells

Fan Yang; Bowei Wang; Jiajia Wang; Yujuan Chen; Zuobin Wang

doi:10.1109/3M-NANO49087.2021.9599761

Multi-parameter AFM characterization of INS-1 cells

Fan Yang
, Bowei Wang
, Jiajia Wang
, Yujuan Chen
, Zuobin Wang

Changchun University of Science and Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

1 Downloads (Pure)

Abstract

AFM-based single cell force spectroscopy has been employed wildly, while more work is needed for the mechanical detection of diabetes-related cells (INS-1 cells). In this study, a multi-parameter AFM characterization was performed to detect the mechanical properties of INS-1 cells in situ. High resolution topographies and concurrent mechanics were obtained by taking the advantage of the quantitatively imaging (QI) mode AFM. The analyses of force curves and force maps jointly presented the multiple parameters involved in the cell mechanics. The AFM force spectroscopy measurement provides full analysis and comprehensive understanding of cell mechanics.

Original language	English
Title of host publication	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	152-155
Number of pages	4
ISBN (Electronic)	9781665448819
ISBN (Print)	9781665448826
DOIs	https://doi.org/10.1109/3M-NANO49087.2021.9599761
Publication status	Published - 17 Nov 2021
Event	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China Duration: 2 Aug 2021 → 6 Aug 2021 http://3m-nano.org/2021/main/index.asp

Publication series

Name	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

Conference

Conference	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
City	Xi'an, China
Period	2/08/21 → 6/08/21
Other	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) (02/08/2021-06/08/2021, Xi'an, China)
Internet address	http://3m-nano.org/2021/main/index.asp

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Force curves
INS-1 Cells
cell mechanics
multi-parameter AFM
force curves

ASJC Scopus subject areas

Industrial and Manufacturing Engineering
Electronic, Optical and Magnetic Materials
Metals and Alloys
Polymers and Plastics
Surfaces, Coatings and Films
Control and Optimization
Instrumentation

Access to Document

10.1109/3M-NANO49087.2021.9599761

17-Multi-parameter AFM Characterization of INS-1 Cells Fan YangAccepted author manuscript, 807 KBLicence: CC BY-NC-ND

https://ieeexplore.ieee.org/document/9599761

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Yang, F., Wang, B., Wang, J., Chen, Y., & Wang, Z. (2021). Multi-parameter AFM characterization of INS-1 cells. In 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings (pp. 152-155). (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/3M-NANO49087.2021.9599761

Yang, Fan ; Wang, Bowei ; Wang, Jiajia et al. / Multi-parameter AFM characterization of INS-1 cells. 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. pp. 152-155 (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings).

@inproceedings{e3733592573d4909812c0c4521b257ce,

title = "Multi-parameter AFM characterization of INS-1 cells",

abstract = "AFM-based single cell force spectroscopy has been employed wildly, while more work is needed for the mechanical detection of diabetes-related cells (INS-1 cells). In this study, a multi-parameter AFM characterization was performed to detect the mechanical properties of INS-1 cells in situ. High resolution topographies and concurrent mechanics were obtained by taking the advantage of the quantitatively imaging (QI) mode AFM. The analyses of force curves and force maps jointly presented the multiple parameters involved in the cell mechanics. The AFM force spectroscopy measurement provides full analysis and comprehensive understanding of cell mechanics.",

keywords = "Force curves, INS-1 Cells, cell mechanics, multi-parameter AFM, force curves",

author = "Fan Yang and Bowei Wang and Jiajia Wang and Yujuan Chen and Zuobin Wang",

note = "Publisher Copyright: {\textcopyright} 2021 IEEE.; 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) ; Conference date: 02-08-2021 Through 06-08-2021",

year = "2021",

month = nov,

day = "17",

doi = "10.1109/3M-NANO49087.2021.9599761",

language = "English",

isbn = "9781665448826",

series = "2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "152--155",

booktitle = "2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings",

address = "United States",

url = "http://3m-nano.org/2021/main/index.asp",

}

Yang, F, Wang, B, Wang, J, Chen, Y & Wang, Z 2021, Multi-parameter AFM characterization of INS-1 cells. in 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings, Institute of Electrical and Electronics Engineers Inc., pp. 152-155, 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO), Xi'an, China, 2/08/21. https://doi.org/10.1109/3M-NANO49087.2021.9599761

Multi-parameter AFM characterization of INS-1 cells. / Yang, Fan; Wang, Bowei; Wang, Jiajia et al.
2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. p. 152-155 (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Multi-parameter AFM characterization of INS-1 cells

AU - Yang, Fan

AU - Wang, Bowei

AU - Wang, Jiajia

AU - Chen, Yujuan

AU - Wang, Zuobin

PY - 2021/11/17

Y1 - 2021/11/17

N2 - AFM-based single cell force spectroscopy has been employed wildly, while more work is needed for the mechanical detection of diabetes-related cells (INS-1 cells). In this study, a multi-parameter AFM characterization was performed to detect the mechanical properties of INS-1 cells in situ. High resolution topographies and concurrent mechanics were obtained by taking the advantage of the quantitatively imaging (QI) mode AFM. The analyses of force curves and force maps jointly presented the multiple parameters involved in the cell mechanics. The AFM force spectroscopy measurement provides full analysis and comprehensive understanding of cell mechanics.

AB - AFM-based single cell force spectroscopy has been employed wildly, while more work is needed for the mechanical detection of diabetes-related cells (INS-1 cells). In this study, a multi-parameter AFM characterization was performed to detect the mechanical properties of INS-1 cells in situ. High resolution topographies and concurrent mechanics were obtained by taking the advantage of the quantitatively imaging (QI) mode AFM. The analyses of force curves and force maps jointly presented the multiple parameters involved in the cell mechanics. The AFM force spectroscopy measurement provides full analysis and comprehensive understanding of cell mechanics.

KW - Force curves

KW - INS-1 Cells

KW - cell mechanics

KW - multi-parameter AFM

KW - force curves

UR - https://www.scopus.com/pages/publications/85123297739

U2 - 10.1109/3M-NANO49087.2021.9599761

DO - 10.1109/3M-NANO49087.2021.9599761

M3 - Conference contribution

SN - 9781665448826

T3 - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

SP - 152

EP - 155

BT - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)

Y2 - 2 August 2021 through 6 August 2021

ER -

Yang F, Wang B, Wang J, Chen Y, Wang Z. Multi-parameter AFM characterization of INS-1 cells. In 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2021. p. 152-155. (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings). doi: 10.1109/3M-NANO49087.2021.9599761

Multi-parameter AFM characterization of INS-1 cells

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

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