Intraarticular injection of allogenic chondroprogenitors for treatment of osteoarthritis in rabbit knee model

Elizabeth Vinod; Jithu Varghese James; Arumugam Sabareeswaran; Soosai Manickam Amirtham; George Thomas; Solomon Sathishkumar; Ozlem Ozbey; P R J V C Boopalan

doi:10.1016/j.jcot.2018.07.003

Intraarticular injection of allogenic chondroprogenitors for treatment of osteoarthritis in rabbit knee model

Elizabeth Vinod
, Jithu Varghese James
, Arumugam Sabareeswaran
, Soosai Manickam Amirtham
, George Thomas
, Solomon Sathishkumar
, Ozlem Ozbey
, P R J V C Boopalan

Christian Medical College
Sree Chitra Tirunal Institute for Medical Sciences and Technology
St. Isabel's Hospital
Akdeniz University

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Osteoarthritis (OA) is the most common disabling degenerative joint disease in humans, characterized by breakdown of cartilage and compensatory overgrowth of bone.1 The prevalent strategies for management of OA include non-operative measures such as life style modification, use of anti-inflammatory drugs, intra-articular injection of lubricants as well as interventional therapies including lavage, debridement, marrow stimulation techniques, transplantation of grafts among others.2 The varied results with these modalities have prompted the search for other treatment options.

Original language	English
Pages (from-to)	16-23
Number of pages	8
Journal	Journal of Clinical Orthopaedics and Trauma
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/j.jcot.2018.07.003
Publication status	Published - 16 Jul 2018
Externally published	Yes

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https://www.journal-cot.com/article/S0976-5662(18)30271-6/abstract

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title = "Intraarticular injection of allogenic chondroprogenitors for treatment of osteoarthritis in rabbit knee model",

abstract = "Osteoarthritis (OA) is the most common disabling degenerative joint disease in humans, characterized by breakdown of cartilage and compensatory overgrowth of bone.1 The prevalent strategies for management of OA include non-operative measures such as life style modification, use of anti-inflammatory drugs, intra-articular injection of lubricants as well as interventional therapies including lavage, debridement, marrow stimulation techniques, transplantation of grafts among others.2 The varied results with these modalities have prompted the search for other treatment options. ",

author = "Elizabeth Vinod and James, \{Jithu Varghese\} and Arumugam Sabareeswaran and Amirtham, \{Soosai Manickam\} and George Thomas and Solomon Sathishkumar and Ozlem Ozbey and Boopalan, \{P R J V C\}",

year = "2018",

month = jul,

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doi = "10.1016/j.jcot.2018.07.003",

language = "English",

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TY - JOUR

T1 - Intraarticular injection of allogenic chondroprogenitors for treatment of osteoarthritis in rabbit knee model

AU - Vinod, Elizabeth

AU - James, Jithu Varghese

AU - Sabareeswaran, Arumugam

AU - Amirtham, Soosai Manickam

AU - Thomas, George

AU - Sathishkumar, Solomon

AU - Ozbey, Ozlem

AU - Boopalan, P R J V C

PY - 2018/7/16

Y1 - 2018/7/16

N2 - Osteoarthritis (OA) is the most common disabling degenerative joint disease in humans, characterized by breakdown of cartilage and compensatory overgrowth of bone.1 The prevalent strategies for management of OA include non-operative measures such as life style modification, use of anti-inflammatory drugs, intra-articular injection of lubricants as well as interventional therapies including lavage, debridement, marrow stimulation techniques, transplantation of grafts among others.2 The varied results with these modalities have prompted the search for other treatment options.

AB - Osteoarthritis (OA) is the most common disabling degenerative joint disease in humans, characterized by breakdown of cartilage and compensatory overgrowth of bone.1 The prevalent strategies for management of OA include non-operative measures such as life style modification, use of anti-inflammatory drugs, intra-articular injection of lubricants as well as interventional therapies including lavage, debridement, marrow stimulation techniques, transplantation of grafts among others.2 The varied results with these modalities have prompted the search for other treatment options.

U2 - 10.1016/j.jcot.2018.07.003

DO - 10.1016/j.jcot.2018.07.003

M3 - Article

C2 - 30705526

SN - 0976-5662

VL - 10

SP - 16

EP - 23

JO - Journal of Clinical Orthopaedics and Trauma

JF - Journal of Clinical Orthopaedics and Trauma

IS - 1

ER -

Intraarticular injection of allogenic chondroprogenitors for treatment of osteoarthritis in rabbit knee model

Abstract

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