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Imaging quality assessment of different AFM working modes on living cancer cells

  • Guoliang Wang
  • , Baishun Sun
  • , Xiaomin Wu
  • , Wenxiao Zhang
  • , Yingmin Qu
  • , Zhengxun Song
  • , Zuobin Wang
  • , Dayou Li
  • Changchun University of Science and Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Since the invention of atomic force microscope (AFM) in 1986, its capabilities in biophysical research, such as living cell imaging, molecule imaging and recognition and drug treatment analysis, have been deeply investigated. Various types of working modes of atomic force microscopy have been employed for imaging and analyzing living cells. The physical properties of living cells can be directly illustrated by its good resolution images. In this paper, the applications of three AFM working modes including contact, tapping and quantitative imaging (QI) modes for the investigation of living lung cancer cells (A549) are presented. Meanwhile, the quality of images of the cells obtained by different working modes is compared through the image quality assessment (IQA) methods.
Original languageEnglish
Title of host publicationnan
PublisherInstitute of Electrical and Electronics Engineers Inc.
DOIs
Publication statusPublished - 2 Feb 2020
Event2019 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Zhenjiang
Duration: 4 Aug 20198 Aug 2019

Conference

Conference2019 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
CityZhenjiang
Period4/08/198/08/19
Other2019 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) (04/08/2019-08/08/2019, Zhenjiang)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • imaging quality assessment

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