Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the Toledo study for healthy aging

Leocadio Rodríguez-Mañas; Laure Carcaillon; F. J. García-García; J. A. F. Tresguerres; G. Gutiérrez Avila; R. Kireev

doi:10.1210/jc.2012-1271

Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the Toledo study for healthy aging

Leocadio Rodríguez-Mañas
, Laure Carcaillon
, F. J. García-García
, J. A. F. Tresguerres
, G. Gutiérrez Avila
, R. Kireev

University of Bedfordshire

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

Adverse effects of higher endogenous estradiol (E2) levels on various clinical outcomes and on determinants of the frailty syndrome have recently been reported. However, there are no data about the potential relationship between E2 and frailty. We aimed to study the association between E2 levels and frailty among older postmenopausal women not taking hormonal therapy.

Original language	English
Pages (from-to)	2898-2906
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	97
Issue number	8
DOIs	https://doi.org/10.1210/jc.2012-1271
Publication status	Published - 1 Aug 2012

Keywords

Frailty

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title = "Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the Toledo study for healthy aging",

abstract = "Adverse effects of higher endogenous estradiol (E2) levels on various clinical outcomes and on determinants of the frailty syndrome have recently been reported. However, there are no data about the potential relationship between E2 and frailty. We aimed to study the association between E2 levels and frailty among older postmenopausal women not taking hormonal therapy.",

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Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the Toledo study for healthy aging. / Rodríguez-Mañas, Leocadio; Carcaillon, Laure; García-García, F. J. et al.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 8, 01.08.2012, p. 2898-2906.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the Toledo study for healthy aging

AU - Rodríguez-Mañas, Leocadio

AU - Carcaillon, Laure

AU - García-García, F. J.

AU - Tresguerres, J. A. F.

AU - Gutiérrez Avila, G.

AU - Kireev, R.

PY - 2012/8/1

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N2 - Adverse effects of higher endogenous estradiol (E2) levels on various clinical outcomes and on determinants of the frailty syndrome have recently been reported. However, there are no data about the potential relationship between E2 and frailty. We aimed to study the association between E2 levels and frailty among older postmenopausal women not taking hormonal therapy.

AB - Adverse effects of higher endogenous estradiol (E2) levels on various clinical outcomes and on determinants of the frailty syndrome have recently been reported. However, there are no data about the potential relationship between E2 and frailty. We aimed to study the association between E2 levels and frailty among older postmenopausal women not taking hormonal therapy.

KW - Frailty

U2 - 10.1210/jc.2012-1271

DO - 10.1210/jc.2012-1271

M3 - Article

SN - 0021-972X

VL - 97

SP - 2898

EP - 2906

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 8

ER -

Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the Toledo study for healthy aging

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