Effect of astragalus polysaccharides on cancer cells studied by AFM

Zhengcheng Lu; Zuobin Wang; Dayou Li; Wenyu Zhu; Rui Wang; Kaige Qu; Jin Yan

doi:10.1109/3M-NANO49087.2021.9599809

Effect of astragalus polysaccharides on cancer cells studied by AFM

Zhengcheng Lu
, Zuobin Wang
, Dayou Li
, Wenyu Zhu
, Rui Wang
, Kaige Qu
, Jin Yan

Changchun University of Science and Technology
University of Bedfordshire

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Citations (Scopus)

3 Downloads (Pure)

Abstract

As a traditional Chinese medicine, astragalus and its products are used in cancer treatment aiming to reduce the side effects of chemotherapy. Cells are the most basic unit of living organisms, and AFM directly obtains information from living cells on the micro/nano scale. Therefore, the use of AFM to study the interaction between astragalus and cells is conducive to a full range of drug efficacy evaluation and provides a new way for drug development. In this paper, astragalus polysaccharides were extracted from astragalus, which were diluted into solutions of different concentrations. Combined with the MTT experiment, the effects of Astragalus polysaccharide on cancer cells and benign cells were studied by AFM.

Original language	English
Title of host publication	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	51-54
Number of pages	4
ISBN (Electronic)	9781665448819
ISBN (Print)	9781665448826
DOIs	https://doi.org/10.1109/3M-NANO49087.2021.9599809
Publication status	Published - 17 Nov 2021
Event	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China Duration: 2 Aug 2021 → 6 Aug 2021 http://3m-nano.org/2021/main/index.asp

Publication series

Name	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

Conference

Conference	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
City	Xi'an, China
Period	2/08/21 → 6/08/21
Other	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) (02/08/2021-06/08/2021, Xi'an, China)
Internet address	http://3m-nano.org/2021/main/index.asp

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

AFM
Astragalus polysaccharides
MTT
cancer cells

ASJC Scopus subject areas

Industrial and Manufacturing Engineering
Electronic, Optical and Magnetic Materials
Metals and Alloys
Polymers and Plastics
Surfaces, Coatings and Films
Control and Optimization
Instrumentation

Access to Document

10.1109/3M-NANO49087.2021.9599809

20-Effect of Astragalus Polysaccharides on Cancer Cells Studied by AFMAccepted author manuscript, 374 KBLicence: CC BY-NC-ND

https://ieeexplore.ieee.org/document/9599809

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Lu, Z., Wang, Z., Li, D., Zhu, W., Wang, R., Qu, K., & Yan, J. (2021). Effect of astragalus polysaccharides on cancer cells studied by AFM. In 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings (pp. 51-54). (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/3M-NANO49087.2021.9599809

Lu, Zhengcheng ; Wang, Zuobin ; Li, Dayou et al. / Effect of astragalus polysaccharides on cancer cells studied by AFM. 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. pp. 51-54 (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings).

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title = "Effect of astragalus polysaccharides on cancer cells studied by AFM",

abstract = "As a traditional Chinese medicine, astragalus and its products are used in cancer treatment aiming to reduce the side effects of chemotherapy. Cells are the most basic unit of living organisms, and AFM directly obtains information from living cells on the micro/nano scale. Therefore, the use of AFM to study the interaction between astragalus and cells is conducive to a full range of drug efficacy evaluation and provides a new way for drug development. In this paper, astragalus polysaccharides were extracted from astragalus, which were diluted into solutions of different concentrations. Combined with the MTT experiment, the effects of Astragalus polysaccharide on cancer cells and benign cells were studied by AFM.",

keywords = "AFM, Astragalus polysaccharides, MTT, cancer cells",

author = "Zhengcheng Lu and Zuobin Wang and Dayou Li and Wenyu Zhu and Rui Wang and Kaige Qu and Jin Yan",

note = "Publisher Copyright: {\textcopyright} 2021 IEEE.; 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) ; Conference date: 02-08-2021 Through 06-08-2021",

year = "2021",

month = nov,

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doi = "10.1109/3M-NANO49087.2021.9599809",

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series = "2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

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booktitle = "2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings",

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Lu, Z, Wang, Z, Li, D, Zhu, W, Wang, R, Qu, K & Yan, J 2021, Effect of astragalus polysaccharides on cancer cells studied by AFM. in 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings, Institute of Electrical and Electronics Engineers Inc., pp. 51-54, 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO), Xi'an, China, 2/08/21. https://doi.org/10.1109/3M-NANO49087.2021.9599809

Effect of astragalus polysaccharides on cancer cells studied by AFM. / Lu, Zhengcheng; Wang, Zuobin; Li, Dayou et al.
2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. p. 51-54 (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Effect of astragalus polysaccharides on cancer cells studied by AFM

AU - Lu, Zhengcheng

AU - Wang, Zuobin

AU - Li, Dayou

AU - Zhu, Wenyu

AU - Wang, Rui

AU - Qu, Kaige

AU - Yan, Jin

PY - 2021/11/17

Y1 - 2021/11/17

N2 - As a traditional Chinese medicine, astragalus and its products are used in cancer treatment aiming to reduce the side effects of chemotherapy. Cells are the most basic unit of living organisms, and AFM directly obtains information from living cells on the micro/nano scale. Therefore, the use of AFM to study the interaction between astragalus and cells is conducive to a full range of drug efficacy evaluation and provides a new way for drug development. In this paper, astragalus polysaccharides were extracted from astragalus, which were diluted into solutions of different concentrations. Combined with the MTT experiment, the effects of Astragalus polysaccharide on cancer cells and benign cells were studied by AFM.

AB - As a traditional Chinese medicine, astragalus and its products are used in cancer treatment aiming to reduce the side effects of chemotherapy. Cells are the most basic unit of living organisms, and AFM directly obtains information from living cells on the micro/nano scale. Therefore, the use of AFM to study the interaction between astragalus and cells is conducive to a full range of drug efficacy evaluation and provides a new way for drug development. In this paper, astragalus polysaccharides were extracted from astragalus, which were diluted into solutions of different concentrations. Combined with the MTT experiment, the effects of Astragalus polysaccharide on cancer cells and benign cells were studied by AFM.

KW - AFM

KW - Astragalus polysaccharides

KW - MTT

KW - cancer cells

UR - https://www.scopus.com/pages/publications/85123303559

U2 - 10.1109/3M-NANO49087.2021.9599809

DO - 10.1109/3M-NANO49087.2021.9599809

M3 - Conference contribution

SN - 9781665448826

T3 - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

SP - 51

EP - 54

BT - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)

Y2 - 2 August 2021 through 6 August 2021

ER -

Lu Z, Wang Z, Li D, Zhu W, Wang R, Qu K et al. Effect of astragalus polysaccharides on cancer cells studied by AFM. In 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2021. p. 51-54. (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings). doi: 10.1109/3M-NANO49087.2021.9599809

Effect of astragalus polysaccharides on cancer cells studied by AFM

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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