Cohort profile: the Children's Health in London and Luton (CHILL) cohort

Helen E. Wood; Rosamund E. Dove; Jasmine Chavda; Grainne Colligan; Louise Cross; Harpal Kalsi; James Scales; Ivelina Tsocheva; Sean Beevers; Bill Day; Monica Fletcher; W. James Gauderman; Jonathan Grigg; Hajar Hajmohammadi; Frank J. Kelly; Borislava Mihaylova; Chris Newby; Gurch Randhawa; Aziz Sheikh; Veronica Toffolutti; Florian Tomini; Esther van Sluijs; Ian S. Mudway; Christopher J. Griffiths

doi:10.1093/ije/dyaf055

Cohort profile: the Children's Health in London and Luton (CHILL) cohort

Helen E. Wood
, Rosamund E. Dove
, Jasmine Chavda
, Grainne Colligan
, Louise Cross
, Harpal Kalsi
, James Scales
, Ivelina Tsocheva
, Sean Beevers
, Bill Day
, Monica Fletcher
, W. James Gauderman
, Jonathan Grigg
, Hajar Hajmohammadi
, Frank J. Kelly
, Borislava Mihaylova
, Chris Newby
, Gurch Randhawa
, Aziz Sheikh
, Veronica Toffolutti

Florian Tomini, Esther van Sluijs, Ian S. Mudway, Christopher J. Griffiths

Queen Mary University of London
University of Oxford
Imperial College London
University of Southern California
University of Nottingham
University of Cambridge

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Abstract

The Children’s Health in London and Luton (CHILL) cohort was established to investigate the impact of London’s Ultra Low Emission Zone (ULEZ) on children’s health. Key strengths of CHILL include: the parallel prospective cohort, natural experimental design in which children living in London (exposed to the ULEZ) and children living in Luton (not exposed to a ULEZ or other major air-pollution control measure) are followed over time and compared; its large size (compared with similar studies) and ethnic diversity; high-resolution air pollution exposure data; and objective physiological measurements of lung function.

Original language	English
Article number	dyaf055
Journal	International Journal of Epidemiology
Volume	54
Issue number	3
DOIs	https://doi.org/10.1093/ije/dyaf055
Publication status	Published - 29 May 2025

Keywords

air pollution
lung function
natural experiment
children
cohort
health impacts

ASJC Scopus subject areas

Epidemiology

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10.1093/ije/dyaf055

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https://academic.oup.com/ije/article/54/3/dyaf055/8153002

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Wood, H. E., Dove, R. E., Chavda, J., Colligan, G., Cross, L., Kalsi, H., Scales, J., Tsocheva, I., Beevers, S., Day, B., Fletcher, M., Gauderman, W. J., Grigg, J., Hajmohammadi, H., Kelly, F. J., Mihaylova, B., Newby, C., Randhawa, G., Sheikh, A., ... Griffiths, C. J. (2025). Cohort profile: the Children's Health in London and Luton (CHILL) cohort. International Journal of Epidemiology, 54(3), Article dyaf055. https://doi.org/10.1093/ije/dyaf055

@article{d653309d78854aa4ae7290caf089f8cf,

title = "Cohort profile: the Children's Health in London and Luton (CHILL) cohort",

abstract = "The Children{\textquoteright}s Health in London and Luton (CHILL) cohort was established to investigate the impact of London{\textquoteright}s Ultra Low Emission Zone (ULEZ) on children{\textquoteright}s health. Key strengths of CHILL include: the parallel prospective cohort, natural experimental design in which children living in London (exposed to the ULEZ) and children living in Luton (not exposed to a ULEZ or other major air-pollution control measure) are followed over time and compared; its large size (compared with similar studies) and ethnic diversity; high-resolution air pollution exposure data; and objective physiological measurements of lung function.",

keywords = "air pollution, lung function, natural experiment, children, cohort, health impacts",

author = "Wood, \{Helen E.\} and Dove, \{Rosamund E.\} and Jasmine Chavda and Grainne Colligan and Louise Cross and Harpal Kalsi and James Scales and Ivelina Tsocheva and Sean Beevers and Bill Day and Monica Fletcher and Gauderman, \{W. James\} and Jonathan Grigg and Hajar Hajmohammadi and Kelly, \{Frank J.\} and Borislava Mihaylova and Chris Newby and Gurch Randhawa and Aziz Sheikh and Veronica Toffolutti and Florian Tomini and \{van Sluijs\}, Esther and Mudway, \{Ian S.\} and Griffiths, \{Christopher J.\}",

year = "2025",

month = may,

day = "29",

doi = "10.1093/ije/dyaf055",

language = "English",

volume = "54",

journal = "International Journal of Epidemiology",

issn = "0300-5771",

publisher = "Oxford University Press",

number = "3",

}

Wood, HE, Dove, RE, Chavda, J, Colligan, G, Cross, L, Kalsi, H, Scales, J, Tsocheva, I, Beevers, S, Day, B, Fletcher, M, Gauderman, WJ, Grigg, J, Hajmohammadi, H, Kelly, FJ, Mihaylova, B, Newby, C, Randhawa, G, Sheikh, A, Toffolutti, V, Tomini, F, van Sluijs, E, Mudway, IS & Griffiths, CJ 2025, 'Cohort profile: the Children's Health in London and Luton (CHILL) cohort', International Journal of Epidemiology, vol. 54, no. 3, dyaf055. https://doi.org/10.1093/ije/dyaf055

TY - JOUR

T1 - Cohort profile: the Children's Health in London and Luton (CHILL) cohort

AU - Wood, Helen E.

AU - Dove, Rosamund E.

AU - Chavda, Jasmine

AU - Colligan, Grainne

AU - Cross, Louise

AU - Kalsi, Harpal

AU - Scales, James

AU - Tsocheva, Ivelina

AU - Beevers, Sean

AU - Day, Bill

AU - Fletcher, Monica

AU - Gauderman, W. James

AU - Grigg, Jonathan

AU - Hajmohammadi, Hajar

AU - Kelly, Frank J.

AU - Mihaylova, Borislava

AU - Newby, Chris

AU - Randhawa, Gurch

AU - Sheikh, Aziz

AU - Toffolutti, Veronica

AU - Tomini, Florian

AU - van Sluijs, Esther

AU - Mudway, Ian S.

AU - Griffiths, Christopher J.

PY - 2025/5/29

Y1 - 2025/5/29

N2 - The Children’s Health in London and Luton (CHILL) cohort was established to investigate the impact of London’s Ultra Low Emission Zone (ULEZ) on children’s health. Key strengths of CHILL include: the parallel prospective cohort, natural experimental design in which children living in London (exposed to the ULEZ) and children living in Luton (not exposed to a ULEZ or other major air-pollution control measure) are followed over time and compared; its large size (compared with similar studies) and ethnic diversity; high-resolution air pollution exposure data; and objective physiological measurements of lung function.

AB - The Children’s Health in London and Luton (CHILL) cohort was established to investigate the impact of London’s Ultra Low Emission Zone (ULEZ) on children’s health. Key strengths of CHILL include: the parallel prospective cohort, natural experimental design in which children living in London (exposed to the ULEZ) and children living in Luton (not exposed to a ULEZ or other major air-pollution control measure) are followed over time and compared; its large size (compared with similar studies) and ethnic diversity; high-resolution air pollution exposure data; and objective physiological measurements of lung function.

KW - air pollution

KW - lung function

KW - natural experiment

KW - children

KW - cohort

KW - health impacts

UR - https://www.scopus.com/pages/publications/105006994487

U2 - 10.1093/ije/dyaf055

DO - 10.1093/ije/dyaf055

M3 - Article

SN - 0300-5771

VL - 54

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

IS - 3

M1 - dyaf055

ER -

Cohort profile: the Children's Health in London and Luton (CHILL) cohort

Abstract

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