Acetaminophen (paracetamol) induces hypothermia during acute cold stress

Josh Foster; Alexis R. Mauger; Andrew Govus; David Hewson; Lee Taylor

doi:10.1007/s40261-017-0560-x

Acetaminophen (paracetamol) induces hypothermia during acute cold stress

Josh Foster
, Alexis R. Mauger
, Andrew Govus
, David Hewson
, Lee Taylor

Loughborough University
University of Kent
Mid Sweden University
Aspetar Orthopaedic and Sports Medicine Hospital

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

1 Downloads (Pure)

Abstract

Acetaminophen is an over-the-counter drug used to treat pain and fever, but it has also been shown to reduce core temperature (Tc) in the absence of fever. However, this side effect is not well examined in humans, and it is unknown if the hypothermic response to acetaminophen is exacerbated with cold exposure.

Original language	English
Pages (from-to)	1055-1065
Journal	Clinical Drug Investigation
Volume	37
Issue number	11
DOIs	https://doi.org/10.1007/s40261-017-0560-x
Publication status	Published - 1 Aug 2017

Keywords

Health
Hypothermia
Medical Sciences
core temperature
paracetemol

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10.1007/s40261-017-0560-x

author's accepted versionAccepted author manuscript, 367 KBLicence: CC BY-NC-ND

https://link.springer.com/article/10.1007/s40261-017-0560-x

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title = "Acetaminophen (paracetamol) induces hypothermia during acute cold stress",

abstract = "Acetaminophen is an over-the-counter drug used to treat pain and fever, but it has also been shown to reduce core temperature (Tc) in the absence of fever. However, this side effect is not well examined in humans, and it is unknown if the hypothermic response to acetaminophen is exacerbated with cold exposure.",

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AU - Foster, Josh

AU - Mauger, Alexis R.

AU - Govus, Andrew

AU - Hewson, David

AU - Taylor, Lee

PY - 2017/8/1

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N2 - Acetaminophen is an over-the-counter drug used to treat pain and fever, but it has also been shown to reduce core temperature (Tc) in the absence of fever. However, this side effect is not well examined in humans, and it is unknown if the hypothermic response to acetaminophen is exacerbated with cold exposure.

AB - Acetaminophen is an over-the-counter drug used to treat pain and fever, but it has also been shown to reduce core temperature (Tc) in the absence of fever. However, this side effect is not well examined in humans, and it is unknown if the hypothermic response to acetaminophen is exacerbated with cold exposure.

KW - Health

KW - Hypothermia

KW - Medical Sciences

KW - core temperature

KW - paracetemol

U2 - 10.1007/s40261-017-0560-x

DO - 10.1007/s40261-017-0560-x

M3 - Article

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VL - 37

SP - 1055

EP - 1065

JO - Clinical Drug Investigation

JF - Clinical Drug Investigation

IS - 11

ER -

Acetaminophen (paracetamol) induces hypothermia during acute cold stress

Abstract

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