A dynamic feedback algorithm of AFM based on cell morphology changes

Can Cheng; Xinyue Wang; Jianjun Dong; Zimin Liu; Zuobin Wang

doi:10.1109/3M-NANO49087.2021.9599830

A dynamic feedback algorithm of AFM based on cell morphology changes

Can Cheng
, Xinyue Wang
, Jianjun Dong
, Zimin Liu
, Zuobin Wang

Changchun University of Science and Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The atomic force microscope (AFM) used in biological research as a powerful tool has been for many years. However, the imaging of living cells is still a problem as the sample is too high and too soft to obtain their accurate morphologies. Especially in the high-speed scanning mode, AFM does not have enough judgments to make accurate measurements at the down part of the sample. In this study, we propose an improved control method to improve the image quality of living human colon cancer cells (SW480) especially in the down part during the scanning.

Original language	English
Title of host publication	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	156-159
Number of pages	4
ISBN (Electronic)	9781665448819
ISBN (Print)	9781665448826
DOIs	https://doi.org/10.1109/3M-NANO49087.2021.9599830
Publication status	Published - 18 Nov 2021
Event	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China Duration: 2 Aug 2021 → 6 Aug 2021 http://3m-nano.org/2021/main/index.asp

Publication series

Name	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

Conference

Conference	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
City	Xi'an, China
Period	2/08/21 → 6/08/21
Other	2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) (02/08/2021-06/08/2021, Xi'an, China)
Internet address	http://3m-nano.org/2021/main/index.asp

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

AFM
Cell morphology
Control method
Living cell imaging

ASJC Scopus subject areas

Industrial and Manufacturing Engineering
Electronic, Optical and Magnetic Materials
Metals and Alloys
Polymers and Plastics
Surfaces, Coatings and Films
Control and Optimization
Instrumentation

Access to Document

10.1109/3M-NANO49087.2021.9599830

18-A Dynamic Feedback Algorithm of AFM based on Cell Morphology ChangesAccepted author manuscript, 413 KBLicence: CC BY-NC-ND

https://ieeexplore.ieee.org/document/9599830

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Cite this

Cheng, C., Wang, X., Dong, J., Liu, Z., & Wang, Z. (2021). A dynamic feedback algorithm of AFM based on cell morphology changes. In 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings (pp. 156-159). (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/3M-NANO49087.2021.9599830

Cheng, Can ; Wang, Xinyue ; Dong, Jianjun et al. / A dynamic feedback algorithm of AFM based on cell morphology changes. 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. pp. 156-159 (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings).

@inproceedings{94849c7ca766444c81402071c5950d81,

title = "A dynamic feedback algorithm of AFM based on cell morphology changes",

abstract = "The atomic force microscope (AFM) used in biological research as a powerful tool has been for many years. However, the imaging of living cells is still a problem as the sample is too high and too soft to obtain their accurate morphologies. Especially in the high-speed scanning mode, AFM does not have enough judgments to make accurate measurements at the down part of the sample. In this study, we propose an improved control method to improve the image quality of living human colon cancer cells (SW480) especially in the down part during the scanning.",

keywords = "AFM, Cell morphology, Control method, Living cell imaging",

author = "Can Cheng and Xinyue Wang and Jianjun Dong and Zimin Liu and Zuobin Wang",

note = "Publisher Copyright: {\textcopyright} 2021 IEEE.; 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) ; Conference date: 02-08-2021 Through 06-08-2021",

year = "2021",

month = nov,

day = "18",

doi = "10.1109/3M-NANO49087.2021.9599830",

language = "English",

isbn = "9781665448826",

series = "2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "156--159",

booktitle = "2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings",

address = "United States",

url = "http://3m-nano.org/2021/main/index.asp",

}

Cheng, C, Wang, X, Dong, J, Liu, Z & Wang, Z 2021, A dynamic feedback algorithm of AFM based on cell morphology changes. in 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings, Institute of Electrical and Electronics Engineers Inc., pp. 156-159, 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO), Xi'an, China, 2/08/21. https://doi.org/10.1109/3M-NANO49087.2021.9599830

A dynamic feedback algorithm of AFM based on cell morphology changes. / Cheng, Can; Wang, Xinyue; Dong, Jianjun et al.
2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. p. 156-159 (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - A dynamic feedback algorithm of AFM based on cell morphology changes

AU - Cheng, Can

AU - Wang, Xinyue

AU - Dong, Jianjun

AU - Liu, Zimin

AU - Wang, Zuobin

PY - 2021/11/18

Y1 - 2021/11/18

N2 - The atomic force microscope (AFM) used in biological research as a powerful tool has been for many years. However, the imaging of living cells is still a problem as the sample is too high and too soft to obtain their accurate morphologies. Especially in the high-speed scanning mode, AFM does not have enough judgments to make accurate measurements at the down part of the sample. In this study, we propose an improved control method to improve the image quality of living human colon cancer cells (SW480) especially in the down part during the scanning.

AB - The atomic force microscope (AFM) used in biological research as a powerful tool has been for many years. However, the imaging of living cells is still a problem as the sample is too high and too soft to obtain their accurate morphologies. Especially in the high-speed scanning mode, AFM does not have enough judgments to make accurate measurements at the down part of the sample. In this study, we propose an improved control method to improve the image quality of living human colon cancer cells (SW480) especially in the down part during the scanning.

KW - AFM

KW - Cell morphology

KW - Control method

KW - Living cell imaging

UR - https://www.scopus.com/pages/publications/85123275687

U2 - 10.1109/3M-NANO49087.2021.9599830

DO - 10.1109/3M-NANO49087.2021.9599830

M3 - Conference contribution

SN - 9781665448826

T3 - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

SP - 156

EP - 159

BT - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)

Y2 - 2 August 2021 through 6 August 2021

ER -

Cheng C, Wang X, Dong J, Liu Z, Wang Z. A dynamic feedback algorithm of AFM based on cell morphology changes. In 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2021. p. 156-159. (2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2021 - Proceedings). doi: 10.1109/3M-NANO49087.2021.9599830

A dynamic feedback algorithm of AFM based on cell morphology changes

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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